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Arcolane (Ketoconazole)

Arcolane is only found in individuals that have used or taken this drug. It is a broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients. [PubChem]Arcolane interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and increased fungal cellular permeability. Other mechanisms may involve the inhibition of endogenous respiration, interaction with membrane phospholipids, inhibition of yeast transformation to mycelial forms, inhibition of purine uptake, and impairment of triglyceride and/or phospholipid biosynthesis. Arcolane can also inhibit the synthesis of thromboxane and sterols such as aldosterone, cortisol, and testosterone.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

Similar Products:
Lexinor, Caverta, Topigen, Lamisil, Contix, Metrocreme, Turimycin, Prazolan, Polibiotic, Amitril, Clomipramine, Amoxibeta, Vikrol, Ectiban, Dazomet, Metronidazole, Proceptin, Biaxin, Esipram, Hymox, Levitra, Anafranil, Antirobe, Becilan, Panmycin, Oxetol, Virless, Flotral, Nozer,

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This study was aimed to investigate the functional role of miR-15a in breast cancer cells in response to DNA damage and to illustrate the possible potential underlying molecular mechanism(s). EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas. CpdA represses androgen-induced activation of both specific and non-specific androgen DNA response elements. Invariance of the dissipative action at ultrahigh strain rates above the strong shock threshold. Neutrophil gelatinase-associated lipocalin accurately predicts renal tubular injury in patients with chronic hepatitis B treated with nucleos(t)ide analogs.

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Three-dimensional finite element models of the canine femur were created. National surveys suggest minority parents frequently communicate via mobile technology, but it is uncertain how amenable they are to receiving health care information in this format. We investigated the effect of contact heterogeneity of pig herds in Sweden due to herd size, between-herd distance and production type.

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Inducibility of aryl hydrocarbon hydroxylase in cultured human lymphocytes: a study of repeatability. In SAP, ICC reduces, with disrupted ultrastructure, and the integrity of network among intestinal nerve, ICC and smooth muscle is impaired, both of which may affect the intestinal functions. However, a repartitioning effect was found with increases in lean tissue and decreases in body fat. Phentolamine (10(-7) M) enhanced the amplitude and the facilitation of the e.j.p., and with the addition of dopamine (10(-6) M) there was a reduction in the amplitude of e.j.p. As the observed altered brain network properties are associated with increased local iron, our findings may reflect secondary neuronal changes due to pathologic processes including oxidative stress.

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The potential usefulness of human leukocyte antigen typing for celiac disease screening: A systematic review and meta-analysis. Contributing factors should also be addressed prior to return to sports.

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Although we found no change in severity of depressive symptoms in BDep patients receiving riluzole compared with placebo, this trial was limited by the relatively high number of subject withdrawals and the small sample size. Digestive intolerance to cereal flour in adults and its prevention by a new method of flour predigestion

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Shoot elongation, leaf production, stem and leaf biomass per shoot and specific leaf area (SLA, cm2 g-1) were determined in five adult plants, randomly selected in each of three light conditions in two forest sites. Using a continuous-wave optical tomography system with 10(8) source-detector pairs, we demonstrate the reconstruction of an absorption image of a phantom consisting of a highly scattering medium containing absorbing inhomogeneities. The effect of disulfide bond introduction and related Cys/Ser mutations on the stability of a cyclohexanone monooxygenase. The small GTP-binding protein Rab12 plays an important role in the initiation of starvation-induced macroautophagy (autophagy) and is activated by the guanine-nucleotide exchange factor DENND3. Several gene detection strategies are presently available to compile an inventory of genes from large genomic regions.

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Effect of stimulus intensity on the rising phase of the nerve action potential in healthy subjects and in patients with peripheral nerve lesions. The X-ray crystal structure of the enzyme bound to the BPT L-159,061 shows that the tetrazole moiety of the inhibitor interacts directly with one of the two zinc atoms in the active site, replacing a metal-bound water molecule. Altogether, our analysis identifies candidate novel key miRNAs regulating networks of significance for normal PCD and malignant plasma cell biology. This study was aimed to comparison of the effects of the chronic use of the Ribavirin and caffeic acid phenethyl ester (CAPE) on the pancreatic damage and hepatotoxicity in rats.

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Finally, the initial milk expressed did not have a significantly greater amount of bacterial contamination than the milk collected later in the milk expression. A microwave oven was used to melt microbiological media, resulting in a substantial reduction of heat generation and considerable savings in time. Long-term clinical results after stent implantation in old obstructed saphenous vein grafts.

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CNT/PDMS-based canal-typed ear electrodes for inconspicuous EEG recording. All three PGs were capable of inhibiting the contractile responses of the vas deferens, but the concentrations required varied considerably: PGE2 was about 700 times more active than PGI2 and about 4600 times more active than 6-keto-PGF1alpha in this respect. In our study, we firstly showed that the expression levels of IGF-I and miR-21 were up-regulated in RCC tissues and cell lines.

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On the mechanism of renaturation of proteins containing disulfide bonds. This drawback may have a significant impact on the management of skeletal injuries, which are frequently associated with chest trauma. Forskolin, a hypotensive diterpine, is assumed to be a potent activator of adenylate cyclase leading to increased levels of cAMP. In contrast, all mutations in the T and CP motifs dramatically reduced RNA binding. Adenocarcinoma of the urachus associated with elevated levels of CA 125.

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Gastrointestinal toxicity is the most frequent adverse effect associated with nonsteroidal anti-inflammatory drug use. Our experience demonstrates that minilaparotomy for sigmoid volvulus is effective and safe. Value of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography in early diagnosis of lung cancer Cell-specific transcriptomic analyses of three-dimensional shoot development in the moss Physcomitrella patens.

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Allergic dermatitis following 2,4-dinitrochlorbenzol in childhood leukemia and solid tumors MR examinations included routinely T1-weighted (TSE, SE), T1-weighted fat-suppressed (TSE, SE), T2 weighted fast turbo spin-echo (UTSE, Haste), T2-weighted fat-suppressed fast turbo spin-echo (SPIR), 2D-cholangiopancreaticography (images were obtained with breath-held) or 3D-cholangiopancreaticography (images were obtained in coronal and axial plane with respiratory triggering).

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The full-length PhyS displayed a K(m) of 83 microM with a kcat of 175.9 min(-1) and the Domain II displayed a K(m) of 474 microM with a kcat of 10.6 min(-1). In this group, 32 million people lack dental insurance and access to public dental services (Medicaid or Medicare), and 7 million of them need dental care. Early life permethrin exposure induces long-term brain changes in Nurr1, NF-kB and Nrf-2. Distinct Protein Expression Profiles of Solid-Pseudopapillary Neoplasms of the Pancreas. Morphological and endoscopic comparisons in the early forms of stomach cancer

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Hydrogen bonding as a modulator of aromaticity and electronic structure of selected ortho-hydroxybenzaldehyde derivatives. Vitamin C (10 mg/kg) given at the time when the extensive tissue damage was in progress aggravated the oxidative damage, while it protected against the damage when given before the initiation of the damage. In most tertiary care centers in the US, a multidisciplinary liver tumor board has become the standard of care and a key component of best practice protocol for patients with HCC. Data in rectal cancer suggest that a prolonged interval between treatment and operation may improve tumoral pathologic response, R0 resection rate, and survival. Levels of prevention: restructuring a curriculum to meet future healthcare needs.

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A 49 year old woman diagnosed as a cervical cancer patient, after receiving appropriate treatment experienced metastasis in her abdominopelvic cavity. Comparative genomic studies based upon a mice model have identified a new resistance-associated protein in human macrophages. Efforts to standardize hand surgery training during plastic surgery residency remain challenging. The role of taxanes as a component of neoadjuvant chemotherapy for breast cancer.

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