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Apcalis (Apcalis) and Viagra (sildenafil) are oral drugs that are used for treating impotence (the inability to attain or maintain a penile erection) and benign prostatic hyperplasia (BPH). They are in a class of drugs called phosphodiesterase-5 (PDE5) inhibitors that also includes vardenafil (Levitra, Staxyn ODT), and avanafil (Stendra). Penile erection is caused by the engorgement of the penis with blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis. Apcalis and Viagra inhibit an enzyme called phosphodiesterase-5 (PDE5) which destroys the cGMP. Thus, Apcalis and Viagra prevent the destruction of cGMP and allows cGMP to accumulate and persist longer. The longer cGMP persists, the more prolonged the engorgement of the penis.

Other names for this medication:
Tadalafil, Adcirca, Apcalis, Cialis, Femalefil, Forzest, Ladialis, Snafi, Tadacip, Tadalafilo, Tadalis, Tadalista, Tadapox, Tadora, Vidalista, Zydalis,

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Specific adsorption of simple organic acids on metal(hydr)oxides: a radiotracer approach. Primary myoepithelioma has not been previously described at this site, and this case highlights this varied family of tumors, emphasizes the need to consider myoepithelial tumor in the differential diagnoses of carcinoma variants occurring in the bowel or mesentery, and also adds to the number of reported myoepithelial neoplasms showing markedly aggressive behavior. The low number of patients examined represents a limit of this study and indicates that further investigation is needed. Postoperatively the child developed diabetes, which is easily managed with small doses of insulin.

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